paricalcitol (Zemplar)
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Indications
- treatment of hyperparathyroidism of chronic kidney disease
- treatment of diabetic nephropathy[2] in combination with ACE inhibitor or ARB
Dosage
Mechanism of action
- activates vitamin D receptor
- reduces albuminuria in patients with diabetic nephropathy[2]
More general terms
Additional terms
References
- ↑ Prescriber's Letter 13(2): 2006 Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=220215&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 2.0 2.1 2.2 de Zeeuw D et al. Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): A randomised controlled trial. Lancet 2010 Nov 6; 376:1543 PMID: https://www.ncbi.nlm.nih.gov/pubmed/21055801