methotrimeprazine; levomepromazine (Nozinan, Levoprome)

Indications

• primarily used in palliative care

Adverse effects

• tardive dyskinesia, akathisia, cardiac arrhythmias, hypotension, neuroleptic malignant syndrome

Laboratory

• methotrimeprazine in specimen
  • methotrimeprazine in gastric fluid
  • methotrimeprazine in serum/plasma
  • methotrimeprazine in urine

Mechanism of action

• non-specific drug
  • blocks adrenergic receptors, dopamine receptors, histamine receptors, muscarinic receptors & serotonin receptors

More general terms

• phenothiazine
• neuroleptic

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=72287