recombinant chaperonin 10

Indications

• treatment-resistant rheumatoid arthritis

* may be used in combination with glucocorticoids &/or disease-modifying antirheumatic drugs (DMARDs)

Dosage

5-10 mg IV twice weekly for 12 weeks

Mechanism of action

• inhibits Toll-like receptors in synovial tissue

More general terms

• 10 kD heat shock protein, mitochondrial
• recombinant protein; chimer