recombinant tissue plasminogen activator (TPA, t-PA, rt-PA,)

Introduction

see alteplase, alteplase

Notes

• alteplase is administered by bolus followed by infusion
• reteplase & tenecteplase are administered by bolus
• tenecteplase has the highest fibrin specificity, retelase the lowest

More general terms

• tissue-type plasminogen activator
• fibrinolytic agent (thrombolytic agent)
• enzymatic agent
• recombinant protein; chimer

More specific terms

• alteplase (Activase)
• reteplase (Retevase)
• tenecteplase (TNKase)

Additional terms

• thrombolytic therapy