immunoglobulin kappa variable 1-12 (IGKV1-12)
Jump to navigation
Jump to search
Function
- V region variable domain of immunoglobulin light chains
- variable domains are assembled by V-(D)-J rearrangement & can then be subjected to somatic hypermutations which, after exposure to antigen & selection, allow affinity maturation for a particular antigen
Structure
- contains 1 Ig-like (immunoglobulin-like) domain
Compartment
Polymorphism
- several alleles
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/A0A0C4DH73.html
- ↑ UniProt PubMed refs
PMID: https://www.ncbi.nlm.nih.gov/pubmed/20176268
PMID: https://www.ncbi.nlm.nih.gov/pubmed/176268
PMID: https://www.ncbi.nlm.nih.gov/pubmed/22158414 - ↑ IMGT/GENE-DB http://www.imgt.org/IMGT_GENE-DB/GENelect?query=2+IGKV1-12&species=homo+sapiens