acetylcholine (nicotinic) Ab antibody in serum

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Indications

Reference interval

< 0.03 nmol/L

Clinical significance

Methods

Radioimmunoassay (RIA)

False positives may occur with muscle relaxants:

Acetylcholine receptor antibody is more sensitive for detection of MG than electromyography (EMG) & is useful for following the response of MG to therapy. If negative & clinical suspicion of MG is high, acetylcholine receptor blocking & acetylcholine receptor modulating antibodies are used as 2nd & 3rd line tests.

Specimen

More general terms

More specific terms

Component of

References

  1. Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 651
  2. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995