papilloma virus 16 Ag in tissue

^[1]^[2]

Indications

cure rate for locally-advanced head & neck cancer associated with HPV is much higher that without^[1]
at least some confusion about p16ink4a & papilloma virus 16 Ag in tissue since it seems HPV may induce expression of p16ink4a in squamous cell head & neck cancers^[2]

↑ ^1.0 ^1.1 Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015
↑ ^2.0 ^2.1 Stephen JK, Divine G, Chen KM et al Significance of p16 in Site-specific HPV Positive and HPV Negative Head and Neck Squamous Cell Carcinoma. Cancer Clin Oncol. 2013;2(1):51-61. PMID: https://www.ncbi.nlm.nih.gov/pubmed/23935769 Free PMC Article