MT-ND1 gene mutation

Clinical significance

• defects in MT-ND1 are a cause of
  • Leber hereditary optic neuropathy
  • MELAS syndrome
  • mitochondrial susceptibility to Alzheimer disease
  • non-insulin-dependent diabetes mellitus (NIDDM)

More general terms

• gene mutation testing; gene mutation analysis

Additional terms

• NADH dehydrogenase subunit-1 (NADH ubiquinone oxidoreductase chain-1, MT-ND1, MTND1, NADH1, ND1)