avibactam/ceftazidime (Avycaz)

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Indications

Contraindications

Dosage

  • 2.5 g IV every 8 hours
  • infuse over 2 hours
  • 5-14 days of therapy

Vials contain Avycaz 2.5 gram, equivalent to ceftazidime 2 gram & avibactam 0.5 gram[3]

Dosage adjustment in renal failure

Adverse effects

Mechanism of action

Notes

  • distributed by Forest Pharmaceuticals Inc

More general terms

Components

References

  1. 1.0 1.1 Kelley KJ, Sofair A, Chavey WE New Combo Antibacterial Approved for Complicated Intra-Abdominal Infections, UTIs Physician's First Watch, Feb 27, 2015 David G. Fairchild, MD, MPH, Editor-in-Chief Massachusetts Medical Society http://www.jwatch.org
    FDA News Release. February 25, 2015 FDA approves new antibacterial drug Avycaz http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm435629.htm
  2. Prescriber's Letter 23(3): 2015 New Drug: Avycaz (Ceftazidime/Avibactam) Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=310525&pb=PRL (subscription needed) http://www.prescribersletter.com
  3. 3.0 3.1 FDA Safety Alert. Sept 22, 2015 Avycaz (ceftazidime and avibactam): Drug Safety Communication
    Dose Confusion and Medication Errors http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm463595.htm