Herpes zoster subunit vaccine

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Dosage

  • two doses were given 2 months apart

Mechanism of action

Notes

  • high efficacy in older adults[1]
  • 97% efficacy, with similar benefits across age groups[1]
  • cost effective in older adults[2]

More general terms

References

  1. 1.0 1.1 1.2 Lal H et al Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults. N Engl J Med. April 28, 2015 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/25916341 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1501184
  2. 2.0 2.1 Le P, Rothberg, MB Cost-effectiveness of the Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults. JAMA Intern Med. Published online January 2, 2018. PMID: https://www.ncbi.nlm.nih.gov/pubmed/29297049 https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2666789
    Najafzadeh M. Evolution of Herpes Zoster Vaccines and Their Economic Value. JAMA Intern Med. Published online January 2, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/29297047 https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2666787