Ebola monoclonal antibody (ZMapp)
Jump to navigation
Jump to search
Indications
- investigational for treatment of Ebola virus
Dosage
- 3 infusions
- coadministration of oral favipiravir[2]
Mechanism of action
- cocktail of 3 chimeric monoclonal antibodies targeting the Ebola virus surface glycoprotein[2]
More general terms
References
- ↑ National Institutes of Health. News Release. Feb 27, 2015 Liberia-U.S. clinical research partnership opens trial to test Ebola treatments. http://www.nih.gov/news/health/feb2015/niaid-27.htm
- ↑ 2.0 2.1 2.2 The PREVAIL II Writing Group, for the Multi-National PREVAIL II Study Team. A randomized, controlled trial of ZMapp for Ebola virus infection. N Engl J Med 2016 Oct 13; 375:1448 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/27732819 <Internet> http://www.nejm.org/doi/10.1056/NEJMoa1604330