nodular sclerosis

Introduction

A form of Hodgkin's lymphoma.

Epidemiology

• most common subtype of Hodgkin's lymphoma in developed countries
• affects females & males equally
• median age of onset at ~28 years

Pathology

• large tumor nodules with lacunar Reed-Sternberg cells surrounded by fibrotic collagen bands

More general terms

• Hodgkin's disease (Hodgkin's lymphoma)
• sclerosis

Additional terms

• sclerotherapy (phlebosclerosis)
• sclerotome