HLA-B*5801 allele
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Indications
- assess risk of hypersensitivity to allopurinol[1]
Clinical significance
- the HLA-B*5801 allele is associated with allopurinol-induced Stevens-Johnson syndrome & toxic epidermal necrolysis in the Han-Chinese population
More general terms
References
- ↑ 1.0 1.1 Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline information for allopurinol and HLA-B. https://www.pharmgkb.org/guideline/PA166105003
- ↑ ARUP Consult: HLA-B*58:01 Genotyping, Allopurinol Hypersensitivity https://arupconsult.com/ati/HLA-B58%253A01%2520Genotyping