sacubitril
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Indications
- used in combination with valsartan for treatment of heart failure
Contraindications
- sacubitril is contraindicated in patients with a history of angioedema[3]
Mechanism of action
- inhibits neprilysin
More general terms
Component of
References
- ↑ McMurray JJV et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med 2014 Aug 30; <PubMed> PMID: https://pubmed.ncbi.nlm.nih.gov/25176015 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1409077
- ↑ FDA News Release. July 7, 2015 FDA approves new drug to treat heart failure http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm453845.htm
- ↑ 3.0 3.1 Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025