pixantrone

Indications

• treatment of adults with multiply relapsed or refractory aggressive non-Hodgkin's B-cell lymphoma, previously treated with rituximab [NGC (NICE)]

Mechanism of action

• inhibits DNA topoisomerase 2

More general terms

• topoisomerase-2 inhibitor

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=134019
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9954944
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=9937618
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=6449873
• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=45262985