CCND1 gene rearrangement

Indications

• evaluation of mantle cell lymphoma

Clinical significance

• chromosomal translocation t(11:14) involving CCND1* is diagnostic for mantle cell lymphoma

* CCND1 (PRAD1) is the gene for cyclin D1

More general terms

• chromosome rearrangement testing

Additional terms

• cyclin D1 (parathyroid adenomatosis-1 [PRAD1] protein or bcl-1 proto-oncogene protein, CCND1, BCL1)
• parathyroid adenomatosis [PRAD]-1 gene, CCND1 or bcl-1