tuberculosis vaccine (M72/AS01E vaccine)
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Indications
- latent tuberculosis (50% effective over 3 years)[1][2]
Dosage
- 2 doses 1 month apart
Mechanism of action
- M72/AS01E vaccine contains 2 M tuberculosis proteins plus an adjuvant used in malaria vaccine & recombinant Herpes zoster vaccine
More general terms
References
- ↑ 1.0 1.1 Van Der Meeren O, Hatherill M, Nduba V et al Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis. N Engl J Med. Sept 25, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30280651 Free Article https://www.nejm.org/doi/full/10.1056/NEJMoa1803484
Bloom BR New Promise for Vaccines against Tuberculosis. N Engl J Med. Sept 25, 2018 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30252629 Free Article https://www.nejm.org/doi/full/10.1056/NEJMe1812483 - ↑ 2.0 2.1 Tait DR, Hatherill M, Van Der Meeren O et al Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis. N Engl J Med. Oct 29, 2019 PMID: https://www.ncbi.nlm.nih.gov/pubmed/31661198 https://www.nejm.org/doi/full/10.1056/NEJMoa1909953