BRCA2 gene mutation

Introduction

see BRCA1/BRCA2 genotyping

Complications

• cumulative risk for breast cancer by age 80
  • 72% in BRCA1 carriers & 69% in BRCA2 carriers
• cumulative risk for ovarian cancer by age 80
  • 44% in BRCA1 carriers & 17% in BRCA2 carriers

More general terms

• BRCA gene mutation (BRACAnalysis CDx)

Additional terms

• BRCA1/BRCA2 genotyping
• BRCA2 gene mutation positive
• breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein, BRCA2, FACD, FANCD1)