betatrophin; angiopoietin-like protein 8; hepatocellular carcinoma-associated protein TD26; TD26; RIFL; C19orf80; lipasin; Angptl-8
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Function
- increases pancreatic beta-cell proliferation[1]
- improves glycemic control (article retracted)[2][3]
Compartment
Expression
- liver
- adipose tissue
Notes
More general terms
References
- ↑ 1.0 1.1 1.2 1.3 Yi P, Park SJ, Melton DA Betatrophin: A Hormone that Controls Pancreatic beta Cell Proliferation. Cell, 25 April 2013 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/23623304 <Internet> http://www.cell.com/abstract/S0092-8674(13)00449-2
- ↑ 2.0 2.1 2.2 Cox AR, Barrandon O, Cai EP et al Resolving Discrepant Findings on ANGPTL8 in beta-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy. PLoS One. 2016 Jul 13;11(7):e0159276. PMID: https://www.ncbi.nlm.nih.gov/pubmed/27410263 Free PMC Article
- ↑ 3.0 3.1 3.2 Yi P, Park JS, Melton DA Retraction Notice to: Betatrophin: A Hormone that Controls Pancreatic Beta-Cell Proliferation Cell. 2016 Dec 27 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/28038792 <Internet> http://www.cell.com/cell/fulltext/S0092-8674(16)31733-0