trafficking protein particle complex subunit 11 (TRAPPC11, C4orf41)

Function

• role in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage
• component of the multisubunit TRAPP complex

Structure

belongs to the TRAPPC11 family

Compartment

• Golgi, cis-Golgi network

Alternative splicing

named isoforms=4

Pathology

• mutations in TRAPPC11 are the cause of limb-girdle muscular dystrophy 2S

More general terms

• protein subunit

Component of

• transport protein particle complex (TRAPP complex)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=60684
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:60684
• OMIM: https://mirror.omim.org/entry/614138
• OMIM: https://mirror.omim.org/entry/615356
• UniProt: http://www.uniprot.org/uniprot/Q7Z392.html