cortisol/pramoxine rectal (Anusol HC, Pramosone, Proctofoam-HC)
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Indications
- symptomatic relief of discomfort associated with hemorrhoids & perianal itching or irritation
Contraindications
pregnancy-category +, ? (Anusol-HC)
Dosage
Ointment or suppository BID/TID PRN.
Anusol contains 1% pramoxine HCl.
Anusol HC includes hydrocortisone:
- apply cream every 6 hours PRN or suppository BID.
Ointment: 1 oz.
Pharmacokinetics
elimination: Not absorbed
Adverse effects
- most common (1-10%)
- itching, dryness, folliculitis, hypopigmentation, contact dermatitis, burning, irritation, secondary infection
Mechanism of action
- glucocorticoid
- inhibiton of nerve impulses
More general terms
References
- ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- ↑ Kaiser Permanente Northern California Regional Drug Formulary, 1998
- ↑ Drug Information & Medication Formulary, Veterans Affairs, Central California Health Care System, 1st ed., Ravnan et al eds, 1998 Department of Veterans Affairs, VA National Formulary