aristolochic acid
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Introduction
Component of the Aristolochia genus of plants.
Uses
- used in Chinese herbal medicines
Adverse effects
- toxin, mutagen
- renal tubulointerstitial disease
- may be cause of Balkan nephropathy
- increased risk of transitional cell carcinoma[3]
More general terms
References
- ↑ Hoang ML et al Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing, Science Translational Medicine, 5: 197ra102, 2013 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23926200
Poon SL et al Genome-wide mutational signatures of aristolochic acid and its application as a screening tool, Science Translational Medicine, 5: 197ra101, 2013 PMID: https://www.ncbi.nlm.nih.gov/pubmed/23926199 - ↑ PubChem: 2236
- ↑ 3.0 3.1 Medical Knowledge Self Assessment Program (MKSAP) 17, American College of Physicians, Philadelphia 2015