ocriplasmin
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Indications
- vitreomacular traction in adults, only if:
- an epiretinal membrane is not present &
- stage 2 full-thickness macular hole with diameter <= 400 uM &/or
- severe symptoms [NGC (NICE)]
Mechanism of action
- recombinant truncated form of human plasmin
More general terms
More specific terms
References
- ↑ Stalmans P et al Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes. N Engl J Med 2012; 367:606-615 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/22894573 <Internet> http://www.nejm.org/doi/full/10.1056/NEJMoa1110823 Huang J et al N Engl J Med 2012; 367:2052-2054 http://www.nejm.org/doi/full/10.1056/NEJMc1211068
- ↑ Jetrea http://www.rxlist.com/jetrea-drug.htm