ovarian dysgenesis 2; X-linked hypergonadotropic ovarian dysgenesis; hypergonadotropic ovarian failure due to ovarian dysgenesis

Pathology

• ovarian failure

Genetics

• associated with defects in GDF9B (BMP15)

Clinical manifestations

• primary amenorrhea
• variable development of secondary sex characteristics

Laboratory

• high serum FSH & serum LH

More general terms

• ovarian dysgenesis
• X-linked disease

Additional terms

• growth/differentiation factor 9B; GDF-9B; bone morphogenetic protein 15; BMP-15 (BMP15 GDF9B)

Database

• OMIM: https://mirror.omim.org/entry/300510