clubfoot (talipes equinovarus)

Genetics

• associated with defects in PITX1
• appears to be a multifactorial trait

Clinical manifestations

• congenital limb deformity defined as
  • fixation of the foot in cavus, adductus, varus, & equinus (i.e. inclined inwards, axially rotated outwards, & pointing downwards) with concomitant soft tissue deformities

may occur in isolation or as part of a syndrome

More general terms

• congenital anomaly (birth defect)

Additional terms

• equinovarus

Database

• OMIM: https://mirror.omim.org/entry/119800