lichen nitidus
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Epidemiology
- uncommon to rare, incidence 0.03% of general population
- affects mostly children & young adults
Pathology
- benign disorder; no associated complications or mortality
- lymphohistiocytic inflammatory cell infiltrate close to epidermis
- granulomas may be present
- basal cell hydrops degeneration
- overlying epidermis is flattened & parakeratotic
Genetics
- familial cases have been described
Clinical manifestations
- generally asymptomatic
- occasional pruritus
- flat-topped, skin-colored papules 1-3 mm
- most common sites of involvement
- trunk
- flexor aspects of upper extremities
- dorsal aspects of hands
- genitalia
- mucous membranes & nails may also be affected
- nail changes include pitting, ridging, splitting, & linear striations
Laboratory
Differential diagnosis
- mimics & can coexist with lichen planus
Management
- no established treatment guidelines
- treat as lichen planus
More general terms
References
- ↑ eMedicine: Lichen Nitidus http://emedicine.medscape.com/article/1123127-overview
- ↑ Mayo Clinic: Lichen Nitidus http://www.mayoclinic.com/health/lichen-nitidus/DS00721