chromosomal translocation t11q13.3:14q32 (mantle cell lymphoma)

Introduction

• chromosomal translocation t(11;14)(q13;q32) involving CCND1 (BCL1) with immunoglobulin gene regions may be a cause of B-lymphocytic malignancy, particularly mantle-cell lymphoma; activation of CCND1 may be oncogenic by directly altering progression through the cell cycle

More general terms

• chromosomal translocation