thyroxine-binding globulin in serum/plasma

Indications

• thyroid disorders
  • hypothyroidism

Reference interval

• 1.2 - 2.5 mg/dL (adult male)
• 1.4 - 3.0 mg/dL (adult female)
• higher levels in infants & children; 3.1 - 5.6 mg/dL (4-12 months of age)

Increases

• acute intermittent porphyria
• hypothyroidism
• liver disease
• pregnancy

Decreases

• acute illness
• acromegaly
• hyperthyroidism
• malnutrition
• nephrotic syndrome
• stress from surgery

Methods

• radioimmunoassay

More general terms

• thyroxine-binding globulin in serum/plasma/blood

Additional terms

• thyroxine-binding globulin; Serpin A7; T4-binding globulin (SERPINA7, TBG)

Component of

• thyroxine (T4)/thyroxine-binding globulin (TBG) in serum/plasma