gabapentin enacarbil (Horizant)
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Indications
- restless legs syndrome (FDA-approved April 2011)
- post-herpetic neuralgia[3]
- partial seizure[3]
Dosage
- 600 mg PO at 5 PM (QD) (extended-release)
Pharmacokinetics
- better absorbed than gabapentin & longer-acting, but no evidence that it works better or is better tolerated than gabapentin[2]
Adverse effects
- carries warning of all anticonvulsants of risk for suicidal ideation
Mechanism of action
- precursor of gabapentin
More general terms
References
- ↑ FDA NEWS RELEASE: April 7, 2011 FDA approves Horizant to treat restless legs syndrome http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm250188.htm
- ↑ 2.0 2.1 Prescriber's Letter 18(6): 2011 Restless Legs Syndrome (subscription needed) http://www.prescribersletter.com
- ↑ 3.0 3.1 3.2 Deprecated Reference