human herpes virus 1 protein ICP0

Function

• targets CDC34/UBE2R1, leading to dynamic interaction with proteasomes
• autoubiquitination of CDC34/UBE2R1 is promoted by ICP0 & leads to degradation by the ubiquitin-proteasomal pathway

More general terms

• viral protein

Additional terms

• Herpes simplex type 1 (HSV-1, HHV-1); human herpesvirus 1