chlorpheniramine/hydrocodone (Tussionex)

Indications

cough suppression

Contraindications

• patients < 6 years of age (due to susceptibility to life-threatening & fatal respiratory depression)

Dosage

every 12 hours as directed

Pharmacokinetics

long-acting

Adverse effects

• respiratory depression

• drug adverse effects of antitussive agent(s)

Mechanism of action

• ;ong-acting hydrocodone-containing cough product

More general terms

• antitussive agent
• pharmacologic combination

Components

• chlorpheniramine (Chlor-Trimeton)
• hydrocodone; dihydrocodeinone (Zohydro ER, Hysingla ER)