nicotinic acid/simvastatin (Simcor)

Indications

• hypercholesterolemia
• not for initial therapy
• reserve for patients who don't reach their goals with either agent alone

Dosage

1-2 tablets/day, maximum 2 tablets/day

Tablets:

• 20 mg of simvastatin
• 3 niacin strengths: 500 mg, 750 mg, & 1000 mg

Adverse effects

• flushing (59%), headache (4.5%), itching (3.2%), nausea (3.2%)
• also see simvastatin & niacin

More general terms

• pharmacologic combination

Components

• nicotinic acid (niacin, vitamin B3, Niaspan)
• simvastatin (Zocor)