miR-21

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Pathology

  • miR-21 is expressed at high levels in many animal & human tumors
  • in mice, switching on or off miR-21 can induce or halt a lymphoblastic lymphoma-type syndrome[1]

More general terms

References

  1. 1.0 1.1 Medina PP et al. OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 2010 Sep 2; 467:86 PMID: https://www.ncbi.nlm.nih.gov/pubmed/20693987