DPYD gene mutation

Clinical significance

• defects in DPYD are the cause of dihydropyrimidine dehydrogenase deficiency
• dihydropyrimidine dehydrogenase plays role in degradation of chemotherapeutic drug 5-fluorouracil

More general terms

• gene mutation testing; gene mutation analysis

Additional terms

• dihydropyrimidine dehydrogenase; DHPDHase; dihydrouracil dehydrogenase; dihydrothymine dehydrogenase (DPD, DPYD)