WT1 gene mutation

Clinical manifestations

• defects in WT1 are the cause of
  • Frasier syndrome
  • genitourinary dysplasia component of WAGR syndrome
  • Wilms tumor 1
  • Denys-Drash syndrome
  • isolated diffuse mesangial sclerosis
  • Meacham syndrome
  • hypospadias

More general terms

• gene mutation testing; gene mutation analysis

Additional terms

• Wilms' tumor protein; WT1 protein (WT1, WT3)
• WT1 mRNA expression in blood/tissue