retinitis pigmentosa type 35 (RP35)

Pathology

• degeneration of retinal photoreceptor cells

Genetics

• associated with defects in SEMA4A

Clinical manifestations

• night vision blindness
• loss of midperipheral visual field
• with progression, peripheral vision is lost
• central vision is eventually lost

More general terms

• retinitis pigmentosa (RP)

Additional terms

• semaphorin-4A; semaphorin-B; sema B (SEMA4A, SEMAB, SEMB, UNQ783/PRO1317)

Database

• OMIM: https://mirror.omim.org/entry/61028