myokymia

Etiology

• successive & rapid contractions of motor units associated with chronic nerve injury
• discharges arise from the peripheral aspects of regenerating nerves

Genetics

• associated with defects in KCNA1 (myokymia isolated type 1)

Clinical manifestations

• a nearly continuous undulation of the body surface overlying the muscle

Diagnostic procedures

• electromyography typically shows continuous motor unit activity ith spontaneous oligo- & multiplet-discharges of high intraburst frequency (myokymic discharges)

Notes

• isolated spontaneous muscle twitches occur in many persons & have no grave significance

More general terms

• sign/symptom

Database

• OMIM: https://mirror.omim.org/entry/160120