myokymia
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Etiology
- successive & rapid contractions of motor units associated with chronic nerve injury
- discharges arise from the peripheral aspects of regenerating nerves
Epidemiology
Genetics
- associated with defects in KCNA1 (myokymia isolated type 1)
Clinical manifestations
- fasciculations (muscle twitching)
- a nearly continuous undulation of the body surface overlying the muscle
Diagnostic procedures
- electromyography typically shows continuous motor unit activity ith spontaneous oligo- & multiplet-discharges of high intraburst frequency (myokymic discharges)
Notes
- isolated spontaneous muscle twitches occur in many persons & have no grave significance
More general terms
References
- ↑ NLM MeSH Browser http://www.nlm.nih.gov/mesh/meshhome.html
- ↑ Adams et al., Principles of Neurology, 6th ed, p1491
- ↑ Banik R, Miller NR. Chronic myokymia limited to the eyelid is a benign condition. J Neuroophthalmol. 2004 Dec;24(4):290-2. PMID: https://pubmed.ncbi.nlm.nih.gov/15662242