folate antagonist; folic acid analog; folic acid antagonist

Uses

• cancer chemotherapy
• antibiotic

Mechanism of action

• inhibits of folate metabolism
• inhibits dihydrofolate reductase

More general terms

• antimetabolite
• enzyme inhibitor

More specific terms

• methotrexate (Rheumatrex, MTX)
• pemetrexed (Alimta, LY231514, Rolazar, Tifolar)
• trimethoprim; TMP (Proloprim, Trimpex)

Additional terms

• folic acid; folate; vitamin B9