dual specificity protein phosphatase 13 isoform MDSP; branching-enzyme interacting DSP; muscle-restricted DSP (DUSP13, BEDP, MDSP)

Function

• dual-specificity protein phosphatase
• inhibited by vanadate

Kinetic parameters:

• KM=7.5 mM for p-nitrophenol phosphate (at pH 6.0)

Structure

• belongs to the protein-tyrosine phosphatase family
• non-receptor class dual specificity subfamily
• contains 1 tyrosine-protein phosphatase domain

Compartment

cytoplasm

Alternative splicing

• named isoforms=5
• alternative promoter usage

Expression

skeletal muscle-specific

More general terms

• dual specificity protein phosphatase 13

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51207
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51207
• UniProt: http://www.uniprot.org/uniprot/Q6B8I1.html