tacrolimus toxicity
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Adverse effects
- nephrotoxicity with hyperkalemia, elevated serum creatinine & hypertension
- neurotoxicity including insomnia, mild tremors, headache, photophobia, hyperesthesia, confusion, seizures, dysarthria, persistent coma
- gastrointestinal symptoms including nausea/vomiting, abdominal pain
- peripheral edema at high to toxic levels