pulse pressure
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Reference interval
30-50 mm Hg
Clinical significance
- single best blood pressure measure in predicting mortality in older people[4]*
- strong predictor of peripheral arterial disease[3]*
- inverse correlation with abdominal aortic aneurysm (AAA)[3]*
* huge study, adults 30 years or older, 5 years follow-up[3]
* association with AAA may be more with increased diastolic BP than pulse pressure[3]
* lowest mortality with systolic pressure < 130 mm Hg & diastolic pressure 80-89 mm Hg[4]
Increases
- aortic insufficiency
- atherosclerosis (hardening of the arteries)
- a wider pulse pressure may be associated with increased cardiovascular mortality[2]
Decreases
More general terms
References
- ↑ Manual of Medical Therapeutics, 28th ed, Ewald & McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 577
- ↑ 2.0 2.1 Panagiotakos DB et al, The relation between pulse pressure and cardiovascular mortality in 12,763 middle-aged men from various parts of the world: a 25-year follow-up of the seven countries study. Arch Intern Med 2005; 165:2142 PMID: https://www.ncbi.nlm.nih.gov/pubmed/16217005
- ↑ 3.0 3.1 3.2 3.3 3.4 Rapsomaniki E et al Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1 25 million people. The Lancet, Volume 383, Issue 9932, pg 1899-1911, 31 May 2014 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/24881994 <Internet> http://www.thelancet.com/journals/lancet/article/PIIS0140-6736%2814%2960685-1/abstract#
- ↑ 4.0 4.1 4.2 Glynn RJ, Chae CU, Guralnik JM et al Pulse Pressure and Mortality in Older People. Arch Intern Med. 2000;160(18):2765-2772 <PubMed> PMID: https://www.ncbi.nlm.nih.gov/pubmed/11025786 <Internet> http://archinte.jamanetwork.com/article.aspx?articleid=485457