Colton blood group

Epidemiology

• approximately 92% of Caucasians are Co(A+B-) (Ala-46),
• approximately 8% are Co(A+B+), & only 0.2% are Co(A-B+) (Val-46)
• Co(A-B-) which is very rare, is due to a complete absence of AQP1

Genetics

AQP1 is responsible for the Colton blood group system

More general terms

• blood group locus