Sorsby fundus dystrophy

Epidemiology

rare

Pathology

• macular disorder
• subretinal neovascularization
• atrophy of the ocular tissues
• macular degeneration, disciform

Genetics

• autosomal dominant
• associated with defects in TIMP3

Clinical manifestations

• age of onset in the fourth decade
• loss of central vision
• generally, macular degeneration (disciform) develops within 6 months to 6 years

More general terms

• genetic disease of the eye
• retinal disease

Additional terms

• macular degeneration

Database

• OMIM: https://mirror.omim.org/entry/136900