ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DEAD box RNA helicase 97 kDa; DEAD box protein 54 (DDX54)

Function

• has RNA-dependent ATPase activity
• represses transcriptional activity of nuclear receptors
• interacts in a hormone-dependent manner with nuclear receptors

ATP + H2O = ADP + phosphate

Structure

• belongs to the DEAD box helicase family, DDX54/DBP10 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus, nucleolus

Alternative splicing

named isoforms=2

More general terms

• DEAD box ATP-dependent helicase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=79039
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:79039
• OMIM: https://mirror.omim.org/entry/611665
• UniProt: http://www.uniprot.org/uniprot/Q8TDD1.html