ethanolamine kinase 1; EKI 1 (ETNK1, EKI1)

Function

• highly specific for ethanolamine phosphorylation
• may be a rate-controlling step in phosphatidylethanolamine biosynthesis
• phospholipid metabolism; phosphatidylethanolamine
• biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3

ATP + ethanolamine = ADP + O-phosphoethanolamine

Structure

• belongs to the choline/ethanolamine kinase family

Compartment

cytoplasm

Expression

• expressed in kidney, liver, placenta, heart, leukocyte, ovary & testis

More general terms

• kinase or ATP-phosphotransferase

Additional terms

• choline/ethanolamine kinase; choline kinase beta; CKB; choline kinase-like protein; ethanolamine kinase; EK; ethanolamine kinase beta; EKB; choline/ethanolamine kinase beta; CKEKB (CHKB, CHETK, CHKL)
• ethanolamine kinase 2; EKI 2; ethanolamine kinase-like protein (ETNK2, EKI2, HMFT1716)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55500
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55500
• OMIM: https://mirror.omim.org/entry/609858
• UniProt: http://www.uniprot.org/uniprot/Q9HBU6.html