miR-33
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Pathology
- miR-33a & miR-33b inhibit production of HDL cholesterol
- antisense oligonucleotides injected subcutaneously into monkeys increases HDL cholesterol & decreases serum triglycerides; effects persist for at least 12 weeks[1]
More general terms
References
- ↑ 1.0 1.1 Rayner KJ et al. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature 2011 Oct 20; 478:404 PMID: https://www.ncbi.nlm.nih.gov/pubmed/22012398