nordiazepam (desmethyldiazepam, nordazepam)

Introduction

Major metabolite of diazepam

Pharmacokinetics

• 1/2 life of 4-5 days

Laboratory

• nordiazepam in specimen
  • nordiazepam in hair
  • nordiazepam in tissue
  • nordiazepam in body fluid
    • nordiazepam in blood
    • nordiazepam in gastric fluid
    • nordiazepam in meconium
    • nordiazepam in saliva
    • nordiazepam in serum/plasma
    • nordiazepam in stool
    • nordiazepam in urine
    • nordiazepam in vitreous fluid

More general terms

• heterocyclic compound, 2 rings
• amide
• pharmacologic metabolite

Additional terms

• cytochrome P450 2C19 (cytochrome P450 2C17, cytochrome P450 11A, mephenytoin 4-hydroxylase, cytochrome P450 254C, CYP2C19)
• cytochrome P450 3A4 (cytochrome P450 C3, nifedipine oxidase, P450-PCN1, NF-25, CYP3A4)
• UDP-glucuronosyltransferase (UDPGT)

Database

• PubChem: http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=2995