centrosomal protein of 120 kD; Cep120; coiled-coil domain-containing protein 100 (CCDC100, CEP120)

Function

• plays a role in the microtubule-dependent coupling of the nucleus & the centrosome
• involved in the processes that regulate centrosome-mediated interkinetic nuclear migration of neural progenitors
• implicated in the migration & self renewal of neural progenitors (putative)
• interacts with TACC2 & TACC3 (putative)
• regulates localization of TACC3 to the centrosome (putative)

Structure

belongs to the CEP120 family

Compartment

centrosome (putative)

Alternative splicing

named isoforms=3

More general terms

• centrosomal protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N960.html