transforming acidic coiled-coil-containing protein 2 (anti Zuai-1, AZU-1, TACC2)

Function

• role in organizing centrosomal microtubules (putative)
• tumor suppressor protein (putative)
• tumor progression marker (putative)
• interacts with microtubules

Structure

• belongs to the TACC family
• contains 1 SPAZ domain (Ser/Pro-rich AZU-1 domain)

Compartment

nucleus, centrosome

Alternative splicing

named isoforms=3

More general terms

• cytoskeletal protein
• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/605302
• UniProt: http://www.uniprot.org/uniprot/O95359.html