eukaryotic translation initiation factor 5A-1-like (eIF-5A-1-like, eIF-5A1-like, eukaryotic initiation factor 5A isoform 1-like, EIF5AL1)

Function

• precise role of eIF-5A in protein biosynthesis is not known, but it functions by promoting the formation of the first peptide bond (putative)
• eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a Lys by the addition of a butylamino group (from spermidine)

Structure

belongs to the eIF-5A family

More general terms

• initiation factor

Database

• UniProt: http://www.uniprot.org/uniprot/Q6IS14.html